I've always loved these philosophical questions. Mainly because I've been thrust into several no win situations before in my life:
Most notably this one:
Tell the truth and be hated. Ignore it and hate myself.
I'm sure many people have faced this same dilemma but aren't consciously aware of the philosophy it represents.
But I always tell the truth. It is easier to be hated by other people than hate myself. I've hated myself for many years in my youth and it's not a good one.
But yeah, in answer to your question I'd sacrifice the one person. Every time.
In Spocks own words: "The needs of the many, outweigh the needs of the few"